Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581713 | 1.00 | KMT2A (0.40) | KMT2ATRPV1RAB9AEGFRALDH1A1 | |
| SCHEMBL6582048 | 0.93 | KMT2A (0.38) | KMT2ATRPV1RAB9A | |
| SCHEMBL6582042 | 0.93 | KMT2A (0.38) | KMT2ATRPV1RAB9A | |
| SCHEMBL6582061 | 0.84 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL6582066 | 0.84 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL6576790 | 0.77 | TRPV1 (0.42) | TRPV1 | |
| SCHEMBL6576794 | 0.77 | TRPV1 (0.42) | TRPV1 | |
| SCHEMBL7980769 | 0.76 | EGFR (0.46) | KMT2ARAB9AEGFRALDH1A1 | |
| SCHEMBL6577207 | 0.76 | KMT2A (0.47) | KMT2ARAB9AEGFRALDH1A1 | |
| SCHEMBL6578828 | 0.75 | KMT2A (0.45) | KMT2ARAB9AEGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |