Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587435 | 0.78 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL5658270 | 0.77 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL4026073 | 0.77 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL116573 | 0.77 | TRPV1 (0.63) | TRPV1 | |
| SCHEMBL6066031 | 0.77 | TRPV1 (0.70) | TRPV1 | |
| SCHEMBL5657627 | 0.76 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL5660097 | 0.76 | TRPV1 (0.71) | TRPV1 | |
| SCHEMBL13316653 | 0.76 | TRPV1 (0.70) | TRPV1 | |
| SCHEMBL21127838 | 0.76 | TRPV1 (0.81) | TRPV1 | |
| SCHEMBL4029219 | 0.75 | TRPV1 (0.67) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478363-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | Abbott Laboratories (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003070247-A1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LABORATORIES (US) | 2003-08-28 | — | — | WO | disclosed |