Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336051 | 0.93 | FFAR1 (0.76) | FFAR4FFAR1APPTHRBPTGER1 | |
| SCHEMBL2840795 | 0.90 | FFAR4 (0.55) | FFAR4FFAR1APPMAPTLMNA | |
| SCHEMBL8890494 | 0.88 | APP (0.61) | FFAR4FFAR1APPPOLBMAPT | |
| SCHEMBL5209587 | 0.88 | APP (0.73) | FFAR4FFAR1APPKDM4EMEN1 | |
| SCHEMBL7822529 | 0.88 | FFAR4 (0.73) | FFAR4FFAR1APPKDM4EKMT2A | |
| SCHEMBL6035750 | 0.86 | MAPT (0.61) | FFAR4APPPOLBMAPTTHRB | |
| SCHEMBL11827307 | 0.85 | FFAR4 (0.64) | FFAR4FFAR1APPPOLBMAPT | |
| SCHEMBL19194094 | 0.84 | APP (0.68) | FFAR4FFAR1APPPOLBMAPT | |
| SCHEMBL13690624 | 0.83 | FFAR4 (1.00) | FFAR4FFAR1 | |
| SCHEMBL13690599 | 0.83 | FFAR4 (0.80) | FFAR4FFAR1PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-5932601-A | USEFUL FOR LOWERING BLOOD SUGAR AND LIPID IN BLOOD | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |