Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.66 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.62 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.62 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.60 |
| ▸ | FAP | Q12884 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583232 | 1.00 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL5110004 | 0.86 | DPP4 (0.71) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL5110008 | 0.86 | DPP4 (0.71) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL13552370 | 0.84 | DPP4 (0.68) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL28878374 | 0.82 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL2739931 | 0.82 | DPP4 (0.76) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL5585976 | 0.79 | DPP4 (0.62) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14392760 | 0.79 | DPP4 (1.00) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL15636202 | 0.79 | DPP4 (1.00) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL15636200 | 0.79 | DPP4 (1.00) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937040-B1 | N-SUBSTITUTED 2-CYANOPYRROLIDINES | NOVARTIS AG (CH) | 2004-07-21 | — | — | EP | disclosed |
| EP-0937040-A2 | N-SUBSTITUTED 2-CYANOPYRROLIDINES | Novartis AG (CH) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998019998-A2 | N-SUBSTITUTED 2-CYANOPYRROLIDINES | NOVARTIS AG (CH) | 1998-05-14 | — | — | WO | disclosed |