Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.80 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | AHR | P35869 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585868 | 0.89 | NPY5R (1.00) | NPY5RNPC1RAB9ANR1I2AHR | |
| SCHEMBL6584656 | 0.86 | NPY5R (0.77) | NPY5RNPC1RAB9ANR1I2AHR | |
| SCHEMBL24867160 | 0.83 | NPY5R (0.67) | NPY5RNPC1RAB9ANR1I2AHR | |
| SCHEMBL6584646 | 0.81 | NPY5R (1.00) | NPY5RNPC1RAB9ANR1I2AHR | |
| SCHEMBL6581862 | 0.78 | NPY5R (0.78) | NPY5R | |
| SCHEMBL6583864 | 0.77 | NPY5R (0.87) | NPY5RNPC1RAB9ANR1I2AHR | |
| SCHEMBL6584650 | 0.76 | NPY5R (1.00) | NPY5RNPC1RAB9ANR1I2AHR | |
| SCHEMBL3500300 | 0.75 | NPC1 (0.63) | NPY5RNPC1RAB9ANR1I2AHR | |
| SCHEMBL3500480 | 0.75 | NPC1 (0.63) | NPY5RNPC1RAB9ANR1I2AHR | |
| SCHEMBL13865106 | 0.74 | NPC1 (0.59) | NPY5RNPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | claimed |
| US-6180653-B1 | EATING DISORDERS; DIETETICS; ANTIDIABETIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-01-30 | — | — | US | claimed |
| EP-0945440-A1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-6180653-B1 | EATING DISORDERS; DIETETICS; ANTIDIABETIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0945440-A1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |