Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3009112 | 1.00 | CHRM5 (0.61) | CHRM5ADRA2CACHEOPRL1OPRM1 | |
| SCHEMBL16102614 | 1.00 | CHRM5 (0.61) | CHRM5ADRA2CACHEOPRL1OPRM1 | |
| SCHEMBL1817532 | 0.89 | CHRM5 (0.44) | CHRM5ADRA2CACHEOPRL1OPRM1 | |
| SCHEMBL8108393 | 0.89 | CHRM5 (0.44) | CHRM5ADRA2CACHEOPRL1OPRM1 | |
| SCHEMBL25602930 | 0.83 | CHRM5 (0.61) | CHRM5ADRA2CACHEOPRL1OPRM1 | |
| SCHEMBL11438671 | 0.81 | CHRM5 (0.58) | CHRM5ADRA2CACHEOPRL1OPRM1 | |
| SCHEMBL16128219 | 0.80 | EBP (0.42) | CHRM5ADRA2C | |
| SCHEMBL31333947 | 0.80 | CHRM5 (0.38) | CHRM5ADRA2COPRM1OPRK1OPRD1 | |
| SCHEMBL16098763 | 0.80 | CHRM3 (0.43) | CHRM5ADRA2CACHESIGMAR1DRD2 | |
| SCHEMBL11596303 | 0.79 | CHRM5 (0.84) | CHRM5ADRA2CACHEOPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |