Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585873 | 0.90 | PARP14 (0.34) | PARP14MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6580579 | 0.88 | SMN1; SMN2 (0.41) | PARP14MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6585979 | 0.88 | KDM4E (0.41) | PARP14TNKSTNKS2 | |
| SCHEMBL989396 | 0.87 | TYMS (0.35) | MEN1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL989399 | 0.87 | TYMS (0.35) | MEN1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL2318167 | 0.82 | MAPT (0.37) | PARP14MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2318171 | 0.82 | MAPT (0.37) | PARP14MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10209681 | 0.80 | MEN1 (0.34) | MEN1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL988729 | 0.80 | MEN1 (0.35) | MEN1ALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL988728 | 0.80 | MEN1 (0.35) | MEN1ALDH1A1MAPTKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155012-B1 | ANTI-CANCER DIHYDROQUINAZOLINE DERIVATIVES | CANCER REC TECH LTD (GB) | 2004-04-14 | — | — | EP | disclosed |
| US-6699861-B1 | ANTI-CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2004-03-02 | — | — | US | disclosed |
| EP-1155012-A1 | ANTI-CANCER DIHYDROQUINAZOLINE DERIVATIVES | Cancer Research Ventures Limited (GB) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050417-A1 | ANTI-CANCER DIHYDROQUINAZOLINE DERIVATIVES | CANCER RESEARCH VENTURES LIMITED (GB) | 2000-08-31 | — | — | WO | disclosed |