Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583987 | 1.00 | KDR (0.52) | KDRMAPTFFAR1PPARGPPARA | |
| SCHEMBL6583665 | 0.89 | KDR (0.49) | KDRMAPTFFAR1PPARGPPARA | |
| SCHEMBL6583671 | 0.89 | KDR (0.49) | KDRMAPTFFAR1PPARGPPARA | |
| SCHEMBL8887495 | 0.87 | PPARG (0.49) | PPARGPPARAPPARD | |
| SCHEMBL4029430 | 0.86 | MAPT (0.50) | KDRMAPTFFAR1PPARGPPARA | |
| SCHEMBL6583866 | 0.86 | MAPT (0.48) | KDRMAPTFFAR1PPARGPPARA | |
| SCHEMBL6584125 | 0.85 | MAPT (0.52) | KDRMAPTFFAR1PPARGPPARA | |
| SCHEMBL6972047 | 0.85 | KDR (0.49) | KDRMAPTFFAR1PPARGPPARA | |
| SCHEMBL6584122 | 0.85 | MAPT (0.52) | KDRMAPTFFAR1PPARGPPARA | |
| SCHEMBL8340640 | 0.85 | KDR (0.49) | KDRMAPTFFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-5932601-A | USEFUL FOR LOWERING BLOOD SUGAR AND LIPID IN BLOOD | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |