Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 19/20 | 0.43 |
| ▸ | EDNRB | P24530 | 15/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676135 | 0.89 | EDNRA (0.46) | EDNRAEDNRB | |
| SCHEMBL6583795 | 0.81 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL6584567 | 0.77 | EDNRA (0.41) | EDNRA | |
| SCHEMBL6588099 | 0.77 | EDNRA (0.45) | EDNRAEDNRB | |
| SCHEMBL6584300 | 0.76 | EDNRA (0.48) | EDNRAEDNRB | |
| SCHEMBL6583937 | 0.71 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL6582784 | 0.70 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL7686474 | 0.70 | EDNRA (0.45) | EDNRAEDNRB | |
| SCHEMBL6584412 | 0.69 | EDNRA (0.60) | EDNRAEDNRB | |
| SCHEMBL6585072 | 0.69 | EDNRA (0.79) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901470-B1 | INDOLE DERIVATIVES USEFUL AS ENDOTHELIN RECEPTOR ANTAGONISTS | PFIZER (US) | 2004-03-31 | — | — | EP | disclosed |