Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.62 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913804 | 0.87 | OPRL1 (0.66) | OPRL1OPRM1OPRK1CACNA1GCACNA1H | |
| SCHEMBL4915166 | 0.83 | OPRL1 (0.74) | OPRL1OPRM1OPRK1CACNA1GCACNA1H | |
| SCHEMBL4918244 | 0.82 | OPRL1 (0.75) | OPRL1OPRM1OPRK1CACNA1GCACNA1H | |
| SCHEMBL4914528 | 0.80 | OPRL1 (0.72) | OPRL1OPRM1OPRK1CACNA1GCACNA1H | |
| SCHEMBL6586004 | 0.80 | OPRL1 (0.66) | OPRL1OPRM1OPRK1CACNA1GCACNA1H | |
| SCHEMBL4940191 | 0.80 | OPRL1 (0.69) | OPRL1OPRM1OPRK1CACNA1GCACNA1H | |
| SCHEMBL4921298 | 0.80 | OPRL1 (0.83) | OPRL1OPRM1OPRK1CACNA1GCACNA1H | |
| SCHEMBL4917717 | 0.80 | OPRL1 (0.75) | OPRL1OPRM1OPRK1CACNA1GCACNA1H | |
| SCHEMBL4909901 | 0.79 | OPRL1 (0.77) | OPRL1OPRM1OPRK1CACNA1GCACNA1H | |
| SCHEMBL4918172 | 0.78 | OPRL1 (0.66) | OPRL1OPRM1OPRK1CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |