Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678329 | 0.91 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL6588182 | 0.90 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL6583727 | 0.89 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6586739 | 0.85 | EDNRA (0.83) | EDNRAEDNRB | |
| SCHEMBL7681190 | 0.84 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7687246 | 0.83 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6583937 | 0.82 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL6587025 | 0.80 | EDNRA (0.83) | EDNRAEDNRB | |
| SCHEMBL6584301 | 0.80 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6585072 | 0.80 | EDNRA (0.79) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901470-B1 | INDOLE DERIVATIVES USEFUL AS ENDOTHELIN RECEPTOR ANTAGONISTS | PFIZER (US) | 2004-03-31 | — | — | EP | disclosed |