Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.81 |
| ▸ | PPARD | Q03181 | 9/20 | 0.81 |
| ▸ | PPARG | P37231 | 5/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582544 | 0.94 | PPARA (0.72) | PPARAPPARDPPARG | |
| SCHEMBL5185069 | 0.93 | PPARA (0.82) | PPARAPPARDPPARG | |
| SCHEMBL6582178 | 0.93 | PPARA (0.81) | PPARAPPARDPPARG | |
| SCHEMBL6583337 | 0.93 | PPARA (0.80) | PPARAPPARDPPARG | |
| SCHEMBL6583565 | 0.91 | PPARA (0.81) | PPARAPPARDPPARG | |
| SCHEMBL6581261 | 0.91 | PPARA (0.81) | PPARAPPARDPPARG | |
| SCHEMBL6585956 | 0.91 | PPARA (0.81) | PPARAPPARDPPARG | |
| SCHEMBL6583153 | 0.91 | PPARA (0.69) | PPARAPPARDPPARG | |
| SCHEMBL6584483 | 0.91 | PPARA (0.71) | PPARAPPARDPPARG | |
| SCHEMBL7465097 | 0.90 | PPARA (0.80) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244642-B1 | SUBSTITUTED OXAZOLES AND THIAZOLES DERIVATIVES AS HPPAR ALPHA ACTIVATORS | GLAXO GROUP LTD (GB) | 2004-04-28 | — | — | EP | claimed |
| US-6518290-B1 | Compounds that activate or otherwise interact with one or more of the PPARs have been implicated in the regulation of triglyceride and cholesterol levels in animal models | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | claimed |
| CN-113189842-B | Preparation method of color filter | 江苏穿越光电科技有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-113189842-A | Preparation method of color filter | 尚健 | 2021-07-30 | — | — | CN | disclosed |
| EP-1244642-B1 | SUBSTITUTED OXAZOLES AND THIAZOLES DERIVATIVES AS HPPAR ALPHA ACTIVATORS | GLAXO GROUP LTD (GB) | 2004-04-28 | — | — | EP | disclosed |
| US-6518290-B1 | Compounds that activate or otherwise interact with one or more of the PPARs have been implicated in the regulation of triglyceride and cholesterol levels in animal models | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | disclosed |
| EP-1244642-A1 | SUBSTITUTED OXAZOLES AND THIAZOLES DERIVATIVES AS HPPAR ALPHA ACTIVATORS | GLAXO GROUP LIMITED (GB) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001040207-A1 | SUBSTITUTED OXAZOLES AND THIAZOLES DERIVATIVES AS HPPAR ALPHA ACTIVATORS | GLAXO GROUP LIMITED (GB) | 2001-06-07 | — | — | WO | disclosed |