Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.64 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.53 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.53 |
| ▸ | RIOK2 | Q9BVS4 | 6/20 | 0.47 |
| ▸ | GSK3A | P49840 | 3/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.44 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584295 | 0.85 | NPY5R (0.68) | NPY5RCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL6582907 | 0.84 | NPY5R (0.67) | NPY5RCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL6585000 | 0.84 | NPY5R (0.65) | NPY5RCCNA2CDK2CCNA1MAPK10 | |
| SCHEMBL6581862 | 0.81 | NPY5R (0.78) | NPY5RCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL6584646 | 0.79 | NPY5R (1.00) | NPY5RCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL6586717 | 0.77 | NPY5R (0.71) | NPY5RCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL6584847 | 0.76 | NPY5R (0.76) | NPY5RCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL6585282 | 0.74 | NPY5R (1.00) | NPY5RCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL6584957 | 0.73 | NPY5R (0.62) | NPY5RCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL6584827 | 0.73 | NPY5R (0.64) | NPY5RCCNB2CCNE2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | claimed |
| US-6180653-B1 | EATING DISORDERS; DIETETICS; ANTIDIABETIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-01-30 | — | — | US | claimed |
| EP-0945440-A1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-6180653-B1 | EATING DISORDERS; DIETETICS; ANTIDIABETIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0945440-A1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |