Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 16/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585543 | 1.00 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7916029 | 0.86 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7916025 | 0.86 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6585871 | 0.85 | PDE4A (0.61) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6587617 | 0.82 | PDE4B (0.58) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6586342 | 0.82 | PDE4A (0.51) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6583627 | 0.78 | PDE4D (0.72) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6582898 | 0.77 | PPARG (0.53) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL4816554 | 0.77 | PDE4A (0.71) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7962694 | 0.75 | PDE4B (0.43) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |