Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585343 | 0.95 | ALOX5AP (0.43) | GPR119ALOX5APFEN1F2RL3 | |
| SCHEMBL7675594 | 0.95 | ALOX5AP (0.43) | GPR119ALOX5APFEN1F2RL3 | |
| SCHEMBL6584863 | 0.92 | ALOX5AP (0.45) | GPR119ALOX5APFEN1UCHL1F2RL3 | |
| SCHEMBL6583255 | 0.92 | ALOX5AP (0.45) | GPR119ALOX5APFEN1UCHL1F2RL3 | |
| SCHEMBL6584643 | 0.92 | ALOX5AP (0.45) | GPR119ALOX5APFEN1UCHL1F2RL3 | |
| SCHEMBL6588750 | 0.89 | ALOX5AP (0.38) | GPR119ALOX5APFEN1 | |
| SCHEMBL6588302 | 0.88 | ALOX5AP (0.39) | GPR119ALOX5APFEN1F2RL3 | |
| SCHEMBL6585258 | 0.88 | ALOX5AP (0.39) | GPR119ALOX5APFEN1F2RL3 | |
| SCHEMBL6583119 | 0.86 | ALOX5AP (0.39) | GPR119ALOX5APFEN1 | |
| SCHEMBL6588458 | 0.86 | ALOX5AP (0.39) | GPR119ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934308-B1 | 3-PYRIDYLOXYMETHYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LAB (US) | 2004-08-11 | — | — | EP | disclosed |