Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5389729 | 0.84 | F10 (0.62) | F10KLKB1KCNH2SMN1; SMN2NPC1 | |
| SCHEMBL3165956 | 0.83 | F10 (0.65) | F10KLKB1KCNH2SMN1; SMN2NPC1 | |
| SCHEMBL4857507 | 0.82 | F10 (0.66) | F10KLKB1KCNH2SMN1; SMN2NPC1 | |
| SCHEMBL5392608 | 0.82 | F10 (0.79) | F10KLKB1KCNH2SMN1; SMN2NPC1 | |
| SCHEMBL5388857 | 0.81 | F10 (0.58) | F10KLKB1KCNH2 | |
| SCHEMBL4848484 | 0.81 | F10 (0.65) | F10KLKB1KCNH2SMN1; SMN2NPC1 | |
| SCHEMBL8356569 | 0.80 | F10 (0.64) | F10KLKB1KCNH2SMN1; SMN2NPC1 | |
| SCHEMBL3166031 | 0.80 | F10 (0.61) | F10KLKB1KCNH2 | |
| SCHEMBL13315125 | 0.80 | SMN1; SMN2 (0.77) | F10KCNH2SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13315095 | 0.80 | F10 (0.73) | F10KCNH2SMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379506-A2 | SUBSTITUTED CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002064567-A2 | SUBSTITUTED CARBOXAMIDES AS INHIBITORS OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2002-08-22 | — | — | WO | disclosed |