Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.57 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.57 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.57 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.39 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560644 | 1.00 | DPP4 (0.57) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL6586024 | 1.00 | DPP4 (0.57) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL13661462 | 0.98 | DPP4 (0.56) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL1871830 | 0.98 | DPP4 (0.56) | DPP4DPP8DPP9FAPDPP7 | |
| Hydrochloric Acid SCHEMBL5435095 | 0.98 | DPP4 (0.56) | DPP4DPP8DPP9FAPDPP7 | |
| Hydrochloric Acid SCHEMBL5435102 | 0.98 | DPP4 (0.56) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL488953 | 0.94 | DPP4 (0.64) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL488954 | 0.94 | DPP4 (0.64) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL1383434 | 0.94 | DPP4 (0.64) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL10326191 | 0.92 | DPP4 (0.62) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272468-B1 | INDOLIN-2-ONE DERIVATIVES, PREPARATION AND THEIR USE AS OCYTOCIN RECEPTOR LIGANDS | SANOFI AVENTIS (FR) | 2004-11-17 | — | — | EP | disclosed |
| EP-1272468-A1 | INDOLIN-2-ONE DERIVATIVES, PREPARATION AND THEIR USE AS OCYTOCIN RECEPTOR LIGANDS | Sanofi-Aventis (FR) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001074775-A1 | INDOLIN-2-ONE DERIVATIVES, PREPARATION AND THEIR USE AS OCYTOCIN RECEPTOR LIGANDS | SANOFI-SYNTHELABO (FR) | 2001-10-11 | — | — | WO | disclosed |