Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426335 | 0.81 | SLC18A3 (0.35) | KDM1ASLC6A2HTR2CSLC6A3 | |
| SCHEMBL27943675 | 0.74 | KDM1A (0.39) | RECQLKDM1AADRB2ATMMAP1LC3B | |
| SCHEMBL18019009 | 0.70 | KDM1A (0.46) | RECQLKDM1AADRB2ATMMAP1LC3B | |
| SCHEMBL4038924 | 0.69 | KDM1A (0.44) | RECQLKDM1AADRB2ATMMAP1LC3B | |
| SCHEMBL17147575 | 0.66 | ESR2 (0.48) | KDM1AADRB2MAP1LC3BSLC6A2HTR2A | |
| SCHEMBL21503504 | 0.66 | ESR2 (0.48) | KDM1AADRB2MAP1LC3BSLC6A2HTR2A | |
| SCHEMBL16938580 | 0.66 | ESR2 (0.48) | KDM1AADRB2MAP1LC3BSLC6A2HTR2A | |
| SCHEMBL17147576 | 0.66 | ESR2 (0.48) | KDM1AADRB2MAP1LC3BSLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL7658988 | 0.66 | KDM1A (0.37) | KDM1AATMMAP1LC3BSLC6A2HTR2A | |
| SCHEMBL21550292 | 0.65 | KDM1A (0.44) | RECQLKDM1AADRB2ATMMAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440067-A1 | N-FORMYL DERIVATIVES OF PAROXETINE | Synthon B.V. (NL) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003044012-A1 | N-FORMYL DERIVATIVES OF PAROXETINE | SYNTHON B.V. (NL) | 2003-05-30 | — | — | WO | disclosed |