Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.58 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585417 | 0.86 | OPRL1 (0.51) | OPRL1OPRM1OPRK1TACR1CYP2D6 | |
| SCHEMBL6585509 | 0.86 | OPRL1 (0.51) | OPRL1OPRM1OPRK1TACR1CYP2D6 | |
| SCHEMBL6585514 | 0.86 | OPRL1 (0.51) | OPRL1OPRM1OPRK1TACR1CYP2D6 | |
| SCHEMBL6587601 | 0.86 | OPRL1 (0.51) | OPRL1OPRM1OPRK1TACR1CYP2D6 | |
| SCHEMBL6585420 | 0.86 | OPRL1 (0.51) | OPRL1OPRM1OPRK1TACR1CYP2D6 | |
| SCHEMBL6586638 | 0.86 | OPRL1 (0.64) | OPRL1OPRM1OPRK1ENPP2PARP1 | |
| SCHEMBL4921253 | 0.81 | OPRL1 (0.81) | OPRL1OPRM1OPRK1ENPP2 | |
| SCHEMBL4921256 | 0.81 | OPRL1 (0.81) | OPRL1OPRM1OPRK1ENPP2 | |
| SCHEMBL4921328 | 0.79 | OPRL1 (0.61) | OPRL1OPRM1OPRK1ENPP2PARP1 | |
| SCHEMBL4910560 | 0.79 | OPRL1 (0.78) | OPRL1OPRM1OPRK1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |