Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.66 |
| ▸ | PPARA | Q07869 | 13/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585532 | 0.91 | PPARG (0.79) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6586240 | 0.91 | PPARG (0.68) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6587649 | 0.90 | PPARG (0.74) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6584568 | 0.89 | PPARG (0.68) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL6587021 | 0.89 | PPARG (0.75) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6582922 | 0.88 | PPARG (0.74) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL6583693 | 0.88 | PPARG (0.74) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL6584159 | 0.88 | PPARG (0.74) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL6052212 | 0.88 | PPARG (0.65) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL6583835 | 0.88 | PPARG (0.65) | PPARGPPARAFFAR1KDRPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |