Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.47 |
| ▸ | PPARA | Q07869 | 15/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585536 | 0.91 | PPARG (0.56) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6586247 | 0.91 | PPARG (0.48) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6587658 | 0.90 | PPARG (0.52) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6584573 | 0.89 | PPARG (0.49) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL6587026 | 0.89 | PPARG (0.54) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL6584166 | 0.88 | PPARG (0.53) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL6583699 | 0.88 | PPARG (0.53) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL6582928 | 0.88 | PPARG (0.53) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL6052215 | 0.88 | PPARG (0.45) | PPARGPPARAFFAR1KDRPPARD | |
| SCHEMBL6583842 | 0.88 | FFAR1 (0.46) | PPARGPPARAFFAR1KDRPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |