Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 15/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 3/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585184 | 0.86 | HPSE (0.43) | PARP1HPSEPLA2G2AALOX15PTGS2 | |
| SCHEMBL6585150 | 0.84 | PARP1 (0.46) | PARP1HPSEPKN1PKN2DHODH | |
| SCHEMBL6803959 | 0.82 | PARP1 (0.65) | PARP1PLA2G2AALOX15PTGS2PKN1 | |
| SCHEMBL6586796 | 0.81 | PKN1 (0.39) | PARP1HPSEPLA2G2AALOX15PTGS2 | |
| SCHEMBL6591596 | 0.81 | PARP1 (0.48) | PARP1HPSEPLA2G2AALOX15PTGS2 | |
| SCHEMBL6586775 | 0.79 | PARP1 (0.46) | PARP1HPSEPLA2G2AALOX15PTGS2 | |
| SCHEMBL6589950 | 0.79 | PKN1 (0.46) | PARP1HPSEPLA2G2AALOX15PTGS2 | |
| SCHEMBL6581295 | 0.78 | AURKB (0.56) | PARP1HPSEPLA2G2AALOX15PTGS2 | |
| SCHEMBL6590709 | 0.78 | PKN1 (0.66) | PARP1HPSEPLA2G2AALOX15PTGS2 | |
| SCHEMBL6588713 | 0.78 | HPSE (0.43) | PARP1HPSEPLA2G2AALOX15PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177178-B1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | ABBOTT GMBH & CO KG (DE) | 2004-12-29 | — | — | EP | disclosed |