SCHEMBL6587346

SCHEMBL6587346

CCCc1nc2c(Cl)cc(F)c(-c3nn(C)c(OC(F)F)c3Cl)c2s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6587158 0.85
SCHEMBL6590953 0.85 SLC34A1 (0.30)
SCHEMBL7913770 0.85 KMT2A (0.35)
SCHEMBL6586722 0.84 SMN1; SMN2 (0.34)
SCHEMBL6589176 0.83 F2RL3 (0.31)
SCHEMBL6590185 0.82
SCHEMBL6591812 0.82
SCHEMBL7913787 0.79 GAA (0.30)
SCHEMBL27524238 0.78
SCHEMBL6589355 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944623-B1 SUBSTITUTED PYRAZOLE-3-YL BENZAZOLES BASF AG (DE) 2004-09-01 EP disclosed
US-6232470-B1 AGRICULTURE BASF AKTIENGESELLSCHAFT (DE) 2001-05-15 US disclosed
EP-0944623-A2 SUBSTITUTED PYRAZOLE-3-YL BENZAZOLES BASF AKTIENGESELLSCHAFT (DE) 1999-09-29 EP disclosed
WO-1998027090-A2 SUBSTITUTED PYRAZOLE-3-YL BENZAZOLES BASF AKTIENGESELLSCHAFT (DE) 1998-06-25 WO disclosed