Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587375 | 1.00 | KCNH2 (0.75) | KCNH2MAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL6583865 | 0.92 | KCNH2 (0.71) | KCNH2MAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL6584210 | 0.92 | KCNH2 (0.71) | KCNH2MAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL6583861 | 0.92 | KCNH2 (0.71) | KCNH2MAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL6584205 | 0.92 | KCNH2 (0.71) | KCNH2MAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL6587659 | 0.91 | KCNH2 (0.77) | KCNH2MAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL6587661 | 0.91 | KCNH2 (0.77) | KCNH2MAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL6584560 | 0.91 | KCNH2 (0.69) | KCNH2MAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL6584563 | 0.91 | KCNH2 (0.69) | KCNH2MAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL6584554 | 0.91 | KCNH2 (0.69) | KCNH2MAPK1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214307-B1 | 4-OXYBENZOPYRAN DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6555574-B1 | Antiarrhythmic agents | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-29 | — | — | US | disclosed |
| EP-1214307-A1 | 4-OXYBENZOPYRAN DERIVATIVE | Nissan Chemical Industries, Ltd. (JP) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021609-A1 | 4-OXYBENZOPYRAN DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |