Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.63 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581846 | 1.00 | PPARG (0.63) | PPARGPPARASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6585666 | 1.00 | PPARG (0.63) | PPARGPPARASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6583839 | 0.89 | PPARG (0.60) | PPARGPPARASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6583831 | 0.89 | PPARG (0.60) | PPARGPPARASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6587789 | 0.88 | PPARG (0.59) | PPARGPPARASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6582138 | 0.88 | PPARG (0.59) | PPARGPPARASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6582149 | 0.88 | PPARG (0.59) | PPARGPPARASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6584001 | 0.88 | PPARG (0.67) | PPARGPPARASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6585691 | 0.86 | PPARG (0.68) | PPARGPPARASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6583975 | 0.84 | PPARG (0.62) | PPARGPPARASMN1; SMN2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |