SCHEMBL6587556

SCHEMBL6587556

CC(C)CCCN1CCC(NC(=O)C(O)(c2ccccc2)C2CCC2)CC1

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 19/20 0.66
CHRM1 P11229 19/20 0.66
CHRM3 P20309 19/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6586895 0.95 CHRM2 (0.68) CHRM2CHRM1CHRM3
SCHEMBL27515276 0.91 CHRM2 (0.63) CHRM2CHRM1CHRM3
SCHEMBL6590415 0.91 CHRM2 (0.63) CHRM2CHRM1CHRM3
SCHEMBL6587811 0.91 CHRM2 (0.63) CHRM2CHRM1CHRM3
Hydrochloric Acid SCHEMBL27481264 0.90 CHRM2 (0.62) CHRM2CHRM1CHRM3
Hydrochloric Acid SCHEMBL27481265 0.90 CHRM2 (0.62) CHRM2CHRM1CHRM3
Hydrochloric Acid SCHEMBL6592489 0.90 CHRM2 (0.62) CHRM2CHRM1CHRM3
SCHEMBL508649 0.89 CHRM2 (0.66) CHRM2CHRM1CHRM3
SCHEMBL508650 0.89 CHRM2 (0.66) CHRM2CHRM1CHRM3
SCHEMBL508651 0.89 CHRM2 (0.66) CHRM2CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823423-B1 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMA CO LTD (JP) 2004-06-16 EP claimed
CN-1188471-A 1,4-disubstituted piepridine derivatives BANYU PHARMA CO LTD (JP) 1998-07-22 CN claimed
EP-0823423-A1 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-02-11 EP claimed
EP-0823423-B1 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMA CO LTD (JP) 2004-06-16 EP disclosed
CN-1188471-A 1,4-disubstituted piepridine derivatives BANYU PHARMA CO LTD (JP) 1998-07-22 CN disclosed
US-5750540-A SIDE EFFECT REDUCTION BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-05-12 US disclosed
EP-0823423-A1 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-02-11 EP disclosed