Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588782 | 0.80 | EPHX1 (0.38) | EPHX1TRPV1KMT2ACHRM2CHRM1 | |
| SCHEMBL5752633 | 0.73 | PI4KA (0.39) | EPHX1CHRM2CHRM1CHRM3SHMT2 | |
| SCHEMBL6583944 | 0.71 | KDR (0.40) | EPHX1TRPV1 | |
| SCHEMBL6810815 | 0.71 | KDR (0.42) | EPHX1KMT2ASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL5753008 | 0.70 | MAPK14 (0.56) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6583491 | 0.70 | KDR (0.39) | EPHX1KMT2AHTTSMN1; SMN2MEN1 | |
| SCHEMBL6589214 | 0.70 | KDR (0.41) | EPHX1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL6586069 | 0.69 | EPHX1 (0.39) | EPHX1TRPV1KMT2ASHMT2HTT | |
| SCHEMBL6598212 | 0.69 | KDR (0.40) | EPHX1 | |
| SCHEMBL6583664 | 0.69 | KDR (0.40) | EPHX1KMT2ASHMT2SMN1; SMN2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004534787-A | — | — | 2004-11-18 | — | — | JP | claimed |
| EP-1414810-A2 | 1,4-DISUBSTITUTED BENZO-FUSED CYCLOALKYL UREA COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-05-06 | — | — | EP | claimed |
| WO-2002098869-A2 | 1,4-DISUBSTITUTED BENZO-FUSED CYCLOALKYL UREA COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | claimed |