Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587891 | 1.00 | EDNRB (0.68) | EDNRBEDNRA | |
| SCHEMBL6151675 | 0.84 | EDNRB (0.83) | EDNRBEDNRA | |
| SCHEMBL6151677 | 0.84 | EDNRB (0.83) | EDNRBEDNRA | |
| SCHEMBL4631444 | 0.83 | EDNRB (0.80) | EDNRBEDNRA | |
| SCHEMBL4631448 | 0.83 | EDNRB (0.80) | EDNRBEDNRA | |
| SCHEMBL4632066 | 0.75 | EDNRA (0.69) | EDNRBEDNRA | |
| SCHEMBL4632061 | 0.75 | EDNRA (0.69) | EDNRBEDNRA | |
| SCHEMBL4632361 | 0.74 | EDNRB (0.79) | EDNRBEDNRA | |
| SCHEMBL4631487 | 0.74 | EDNRA (1.00) | EDNRBEDNRA | |
| SCHEMBL6151109 | 0.73 | EDNRA (0.75) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946552-B1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | ENCYSIVE PHARMACEUTICALS INC (US) | 2004-07-07 | — | — | EP | disclosed |