Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588007 | 1.00 | CETP (0.59) | CETP | |
| SCHEMBL6466970 | 0.92 | CETP (0.64) | CETP | |
| SCHEMBL6393852 | 0.91 | CETP (0.72) | CETP | |
| SCHEMBL992791 | 0.91 | CETP (0.72) | CETP | |
| SCHEMBL6587367 | 0.89 | CETP (0.62) | CETP | |
| SCHEMBL6587372 | 0.89 | CETP (0.62) | CETP | |
| SCHEMBL6591589 | 0.89 | CETP (0.56) | CETP | |
| SCHEMBL6591584 | 0.89 | CETP (0.56) | CETP | |
| SCHEMBL6587814 | 0.88 | CETP (0.60) | CETP | |
| SCHEMBL6587815 | 0.88 | CETP (0.60) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114033-B1 | 4-CARBOXYAMINO-2-METHYL-1,2,3,4-TETRAHYDROQUINOLINES AS CETP INHIBITORS | PFIZER PROD INC (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6395751-B1 | SYNERGISTIC MIXTURE; ANTICHOLESTEROL AGENTS | PFIZER INC. | 2002-05-28 | — | — | US | disclosed |
| US-6147090-A | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS USED TO TREAT DISEASES WHICH ARE EXACERBATED BY LOW LEVELS OF HDL CHOLESTEROL AND/OR HIGH LEVELS OF LDL-CHOLESTEROL AND TRIGLYCERIDES, SUCH AS ATHEROSCLEROSIS AND CARDIOVASCULAR | PFIZER INC. (US) | 2000-11-14 | — | — | US | disclosed |