SCHEMBL6588935

SCHEMBL6588935

CN(CCO)Cc1csc(C(=O)Nc2c(OCCCN3CCCC3)cc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c1Cl

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F2 P00734 20/20 0.80
F10 P00742 17/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6592704 0.97 F2 (0.81) F2F10
SCHEMBL6591494 0.95 F2 (0.74) F2F10
SCHEMBL6590401 0.94 F2 (0.86) F2F10
SCHEMBL6591643 0.91 F2 (0.88) F2F10
SCHEMBL6591071 0.89 F2 (0.82) F2F10
SCHEMBL6590042 0.89 F2 (1.00) F2F10
SCHEMBL6593466 0.89 F2 (0.87) F2F10
SCHEMBL6591189 0.88 F2 (0.81) F2F10
SCHEMBL6592667 0.87 F2 (0.73) F2F10
SCHEMBL6587464 0.87 F2 (0.87) F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1040108-B1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AG (DE) 2004-02-25 EP claimed
EP-1040108-B1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AG (DE) 2004-02-25 EP disclosed
US-6498185-B1 ENZYME FACTOR XA INHIBITORS BERLEX LABORATORIES, INC. 2002-12-24 US disclosed
US-6380221-B1 FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY BERLEX LABORATORIES, INC. 2002-04-30 US disclosed
US-6140351-A FOR TREATING THROMBOSIS BERLEX LABORATORIES, INC. (US) 2000-10-31 US disclosed