Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475384 | 0.94 | KCNA3 (0.58) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL29054813 | 0.85 | KCNA3 (0.64) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL29054932 | 0.84 | KCNA3 (0.62) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL29054826 | 0.81 | KCNA3 (0.66) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL29054926 | 0.80 | KCNA3 (0.64) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL29054840 | 0.80 | KCNA3 (0.64) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL29054860 | 0.80 | HDAC1 (0.66) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL6599915 | 0.80 | KCNA3 (0.72) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL14473803 | 0.80 | KCNA3 (0.63) | KCNA3CA12CA1CA9ALOX15 | |
| SCHEMBL29054833 | 0.79 | HDAC1 (0.68) | KCNA3CA12CA1CA9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689799-B1 | NON-NUCLEOSIDE-DERIVATIVE VIRICIDES | REPHARTOX (NL) | 2004-02-10 | — | — | US | disclosed |
| EP-1214315-B9 | 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF | REPHARTOX (NL) | 2004-01-02 | — | — | EP | disclosed |
| EP-1214315-B1 | 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF | REPHARTOX (NL) | 2003-05-02 | — | — | EP | disclosed |
| EP-1214315-A1 | 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF | Rephartox (NL) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001014370-A1 | 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF | REPHARTOX (NL) | 2001-03-01 | — | — | WO | disclosed |