SCHEMBL6589478

SCHEMBL6589478

CN/C(=N/CCN)N(C#N)Cc1csc(C(=O)Nc2c(OC)cc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c1Cl

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.67
F2 P00734 19/20 0.66
KLKB1 P03952 1/20 0.66
ELANE P08246 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6592890 0.91 F2 (0.71) F10F2KLKB1ELANE
SCHEMBL6592308 0.91 F2 (0.71) F10F2KLKB1ELANE
SCHEMBL6589484 0.88 F10 (0.67) F10F2KLKB1ELANE
SCHEMBL6588955 0.84 F2 (0.80) F10F2KLKB1ELANE
SCHEMBL6588965 0.82 F2 (0.81) F10F2KLKB1ELANE
SCHEMBL6593111 0.82 F2 (0.76) F10F2KLKB1ELANE
SCHEMBL6593116 0.82 F2 (0.76) F10F2KLKB1ELANE
SCHEMBL6589493 0.82 F10 (0.68) F10F2KLKB1ELANE
SCHEMBL6590183 0.81 F2 (0.86) F10F2KLKB1ELANE
SCHEMBL6593428 0.81 F10 (1.00) F10F2KLKB1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1040108-B1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AG (DE) 2004-02-25 EP claimed
EP-1040108-B1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AG (DE) 2004-02-25 EP disclosed