⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587175 | 0.93 | — | — | |
| SCHEMBL6592817 | 0.91 | CA1 (0.47) | — | |
| SCHEMBL6588342 | 0.91 | CA1 (0.47) | — | |
| SCHEMBL6590169 | 0.84 | — | — | |
| SCHEMBL6590761 | 0.81 | — | — | |
| SCHEMBL28283616 | 0.79 | NPC1 (0.41) | — | |
| SCHEMBL6591939 | 0.78 | NPC1 (0.41) | — | |
| SCHEMBL10232349 | 0.75 | — | — | |
| SCHEMBL16151463 | 0.75 | — | — | |
| SCHEMBL21006006 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849219-A | Blocked polyisocyanates composition based on 1,5 pentamethylene diisocyanates | 科思创德国股份有限公司 | 2018-03-27 | — | — | CN | claimed |
| CN-109809990-A | A method of 2- oxocyclopentyl ethyl acetate is prepared by esterification | 雷萌 | 2019-05-28 | — | — | CN | disclosed |
| CN-109809990-A | A method of 2- oxocyclopentyl ethyl acetate is prepared by esterification | 雷萌 | 2019-05-28 | — | — | CN | disclosed |
| CN-106008322-B | sulfonamide derivatives as BC L-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE 公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-107849219-A | Blocked polyisocyanates composition based on 1,5 pentamethylene diisocyanates | 科思创德国股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-102307872-B | BCL-2-selectively apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE 公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-104311472-A | Substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives | ARENA PHARM INC | 2015-01-28 | — | — | CN | disclosed |
| CN-102164891-B | Substituted 1,2,3, 4-tetrahydrocyclopenta [ b ] indol-3-yl acetic acid derivatives useful for the treatment of autoimmune and inflammatory diseases | ARENA PHARM INC | 2014-09-03 | — | — | CN | disclosed |
| CN-103058870-A | Preparation method of ethyl 2-oxocyclopentylacetate | UNIV CHINA PHARMA | 2013-04-24 | — | — | CN | disclosed |
| CN-102164891-A | Substituted 1,2,3, 4-tetrahydrocyclopenta [ b ] indol-3-yl acetic acid derivatives useful for the treatment of autoimmune and inflammatory diseases | ARENA PHARM INC | 2011-08-24 | — | — | CN | disclosed |
| CN-1244865-A | Substituted pyrazole-3-yl benzazoles | BASF AK (DE) | 2000-02-16 | — | — | CN | disclosed |
| WO-1999055702-A1 | SUBSTITUTED (4-BROMPYRAZOLE-3-YL)BENZAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-04 | — | — | WO | disclosed |
| EP-0944623-A2 | SUBSTITUTED PYRAZOLE-3-YL BENZAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| EP-0931072-A1 | 1-SULFONYL-3-PHENYLPYRAZOLES AND THEIR USE AS HERBICIDES AND FOR DESICCATING OR DEFOLIATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-28 | — | — | EP | disclosed |
| WO-1999006394-A1 | SUBSTITUTED 2-(BENZOARYL)PYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-11 | — | — | WO | disclosed |
| EP-0862558-A1 | SUBSTITUTED 4,5-DI(TRIFLUOROMETHYL)PYRAZOLES AND THEIR USE AS HERBICIDES AND FOR DESICCATING/DEFOLIATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1998027090-A2 | SUBSTITUTED PYRAZOLE-3-YL BENZAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |
| WO-1998012182-A1 | 1-SULFONYL-3-PHENYLPYRAZOLES AND THEIR USE AS HERBICIDES AND FOR DESICCATING OR DEFOLIATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-26 | — | — | WO | disclosed |
| WO-1997015559-A1 | SUBSTITUTED 4,5-DI(TRIFLUOROMETHYL)PYRAZOLES AND THEIR USE AS HERBICIDES AND FOR DESICCATING/DEFOLIATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |
| CN-87106833-A | Heterogeneous ring compound | — | 1988-04-27 | — | — | CN | disclosed |