Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 6/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590373 | 1.00 | GRN (0.45) | GRNSORT1CCR1PSMB5CNR2 | |
| SCHEMBL6588642 | 0.92 | GRN (0.47) | GRNSORT1CCR1PSMB5CNR2 | |
| SCHEMBL6588637 | 0.92 | GRN (0.47) | GRNSORT1CCR1PSMB5CNR2 | |
| SCHEMBL6611213 | 0.91 | GRN (0.44) | GRNSORT1CCR1PSMB5CNR2 | |
| SCHEMBL6611219 | 0.91 | GRN (0.44) | GRNSORT1CCR1PSMB5CNR2 | |
| SCHEMBL6634574 | 0.87 | GRN (0.52) | GRNSORT1CCR1PSMB5CNR2 | |
| SCHEMBL4763062 | 0.86 | GRN (0.47) | GRNSORT1CCR1PSMB5CNR2 | |
| SCHEMBL4761986 | 0.85 | GRN (0.47) | GRNSORT1CCR1PSMB5CNR2 | |
| SCHEMBL4765859 | 0.85 | GRN (0.47) | GRNSORT1CCR1PSMB5CNR2 | |
| SCHEMBL4770999 | 0.85 | GRN (0.47) | GRNSORT1CCR1PSMB5CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |