SCHEMBL6590397

SCHEMBL6590397

CC(C)(C)OC(=O)N(C[C@@H](O)c1cccc(Cl)c1)[C@H]1CCc2ccc(Oc3cccc(C(=O)O)c3)cc2C1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 20/20 0.63
ADRB1 P08588 10/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6590393 1.00 ADRB3 (0.63) ADRB3ADRB1
SCHEMBL6134084 0.93 ADRB3 (0.62) ADRB3ADRB1
SCHEMBL6134081 0.93 ADRB3 (0.62) ADRB3ADRB1
SCHEMBL6134648 0.92 ADRB3 (0.55) ADRB3ADRB1
SCHEMBL6134650 0.92 ADRB3 (0.55) ADRB3ADRB1
SCHEMBL6589255 0.91 ADRB3 (0.51) ADRB3ADRB1
SCHEMBL6589250 0.91 ADRB3 (0.50) ADRB3ADRB1
SCHEMBL6134484 0.90 ADRB3 (0.63) ADRB3ADRB1
SCHEMBL6134480 0.90 ADRB3 (0.63) ADRB3ADRB1
SCHEMBL6134774 0.90 ADRB3 (0.53) ADRB3ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1483236-A1 AMINOALCOHOL DERIVATIVES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-12-08 EP disclosed
WO-2003076397-A1 AMINOALCOHOL DERIVATIVES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-09-18 WO disclosed