Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252107 | 0.97 | CA1 (0.46) | CA1CA2CA4ALDH1A1NOS3 | |
| SCHEMBL6250904 | 0.97 | CA1 (0.46) | CA1CA2CA4ALDH1A1NOS3 | |
| SCHEMBL598869 | 0.97 | CA1 (0.46) | CA1CA2CA4ALDH1A1NOS3 | |
| SCHEMBL7724695 | 0.97 | CA1 (0.46) | CA1CA2CA4ALDH1A1NOS3 | |
| SCHEMBL6898227 | 0.97 | CA1 (0.46) | CA1CA2CA4ALDH1A1NOS3 | |
| SCHEMBL23952890 | 0.97 | CA1 (0.46) | CA1CA2CA4ALDH1A1NOS3 | |
| SCHEMBL6897202 | 0.97 | CA1 (0.46) | CA1CA2CA4ALDH1A1NOS3 | |
| SCHEMBL4616915 | 0.97 | CA1 (0.46) | CA1CA2CA4ALDH1A1NOS3 | |
| SCHEMBL6894837 | 0.97 | CA1 (0.46) | CA1CA2CA4ALDH1A1NOS3 | |
| SCHEMBL283721 | 0.97 | CA1 (0.46) | CA1CA2CA4ALDH1A1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502839-B1 | Functionalized polymers | MONSANTO CO (US) | 1997-07-09 | — | — | EP | claimed |
| US-5294675-A | A-C copoly;hydroformylation | MONSANTO COMPANY (US) | 1994-03-15 | — | — | US | claimed |
| US-5232989-A | Hydroformylation of polyoefins, reduction to hydroxyl groups, reacting with diisocyanate | MONSANTO COMPANY (US) | 1993-08-03 | — | — | US | claimed |
| EP-0502839-A2 | Functionalized polymers | MONSANTO COMPANY (US) | 1992-09-09 | — | — | EP | claimed |
| WO-2018087126-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES AS INHIBITORS OF TANKYRASE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-17 | — | — | WO | disclosed |
| EP-3287443-A1 | 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Shionogi & Co., Ltd (JP) | 2018-02-28 | — | — | EP | disclosed |
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6140338-A | FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS | BANYU PHARMACEUTICAL, CO., LTD. (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0916668-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0912644-A1 | COATING AGENT ON THE BASIS OF A POLYACRYLATE RESIN CONTAINING AN HYDROXYL GROUP, AND ITS USE IN A METHOD OF PRODUCING A MULTIPLE-LAYER PAINT COATING | BASF Coatings AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |
| WO-1998004642-A1 | COATING AGENT ON THE BASIS OF A POLYACRYLATE RESIN CONTAINING AN HYDROXYL GROUP, AND ITS USE IN A METHOD OF PRODUCING A MULTIPLE-LAYER PAINT COATING | BASF COATINGS AG (DE) | 1998-02-05 | — | — | WO | disclosed |