Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592160 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10MAPKAPK2 | |
| SCHEMBL6598621 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10MAPKAPK2 | |
| SCHEMBL6598618 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10MAPKAPK2 | |
| SCHEMBL6666941 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDMAPKAPK2TNF | |
| SCHEMBL6666936 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDMAPKAPK2TNF | |
| SCHEMBL6595136 | 0.80 | KDM4E (0.65) | KDM4EALDH1A1HPGDTNFRAB9A | |
| SCHEMBL6595131 | 0.80 | KDM4E (0.65) | KDM4EALDH1A1HPGDTNFRAB9A | |
| SCHEMBL6592328 | 0.80 | TNF (0.71) | KDM4EALDH1A1HPGDHSD17B10MAPKAPK2 | |
| SCHEMBL6592329 | 0.80 | TNF (0.71) | KDM4EALDH1A1HPGDHSD17B10MAPKAPK2 | |
| SCHEMBL6595103 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1TNFRAB9ANOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |