Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.37 |
| ▸ | F10 | P00742 | 9/20 | 0.37 |
| ▸ | F3 | P13726 | 12/20 | 0.35 |
| ▸ | F7 | P08709 | 3/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590932 | 0.90 | F10 (0.35) | F2F10F3F7F11 | |
| SCHEMBL6596602 | 0.89 | F2 (0.37) | F2F10F3 | |
| SCHEMBL6591583 | 0.89 | F2 (0.48) | F2F10F3F7F11 | |
| SCHEMBL6587497 | 0.89 | F10 (0.36) | F2F10F3F7F11 | |
| SCHEMBL6590237 | 0.89 | F2 (0.36) | F2F10F3 | |
| SCHEMBL6591343 | 0.88 | FFAR1 (0.38) | F2F10 | |
| SCHEMBL6594081 | 0.86 | F3 (0.33) | F2F10F3F7F11 | |
| SCHEMBL6588980 | 0.85 | F7 (0.40) | F2F10F3F7F11 | |
| SCHEMBL7414064 | 0.85 | F2 (0.37) | F2F10F3F7 | |
| SCHEMBL7414067 | 0.83 | F10 (0.36) | F2F10F3F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888271-B1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | BERLEX LAB (US) | 2004-04-28 | — | — | EP | disclosed |
| US-6242454-B1 | Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants | BERLEX LABORATORIES INC. | 2001-06-05 | — | — | US | disclosed |
| US-6166088-A | CONTROLLING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-12-26 | — | — | US | disclosed |
| US-6071912-A | INHIBIT HUMAN FACTOR XA AND ARE THEREFORE USEFUL AS PHARMACOLOGICAL AGENTS FOR THE TREATMENT OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY; AMINO-, OXY- AND THIA-SUBSTITUTED TRIAZINES | BERLEX LABORATORIES, INC. (US) | 2000-06-06 | — | — | US | disclosed |