Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.54 |
| ▸ | F2 | P00734 | 9/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595675 | 0.87 | F10 (0.52) | F10F2HCRTR1HCRTR2KDM4E | |
| SCHEMBL6590035 | 0.87 | HCRTR1 (0.54) | F10F2HCRTR1HCRTR2KDM4E | |
| SCHEMBL6601695 | 0.85 | F10 (0.53) | F10F2ADORA1HDAC6KDM4E | |
| Hydrochloric Acid SCHEMBL6590659 | 0.84 | F10 (0.53) | F10F2ADORA1HDAC6KDM4E | |
| SCHEMBL27457202 | 0.77 | HCRTR1 (0.40) | F10F2HCRTR1HCRTR2KDM4E | |
| SCHEMBL6591889 | 0.75 | KMT2A (0.39) | F10KDM4E | |
| SCHEMBL6587977 | 0.75 | KMT2A (0.39) | F10KDM4E | |
| SCHEMBL3306728 | 0.74 | KMT2A (0.41) | F10KDM4E | |
| SCHEMBL27595508 | 0.74 | F10 (0.42) | F10F2KDM4E | |
| SCHEMBL27472593 | 0.72 | KMT2A (0.40) | F10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143855-C | I (ortho)-anthranilamide derivatives as anti-coagulants | ���ֹɷݹ�˾ | 2004-03-31 | — | — | CN | disclosed |
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| CN-1282329-A | I (ortho)-anthranilamide derivatives as anti-coagulants | SCHERING AG (DE) | 2001-01-31 | — | — | CN | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-1040108-A1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032477-A1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-07-01 | — | — | WO | disclosed |