SCHEMBL6592241

SCHEMBL6592241

Cc1ccc(NC(=O)c2sc3ccccc3c2Cl)c(C(=O)Nc2ccc(Br)cc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 1.00
TP53 P04637 1/20 0.69
MAPT P10636 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
RXFP1 Q9HBX9 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6591396 0.92 F10 (1.00) F10
SCHEMBL6590511 0.92 F10 (1.00) F10TP53MAPTSMN1; SMN2RXFP1
SCHEMBL6591033 0.90 F10 (0.88) F10
SCHEMBL6590329 0.89 F10 (1.00) F10TP53MAPTSMN1; SMN2RXFP1
SCHEMBL6594123 0.88 F10 (0.89) F10TP53MAPTSMN1; SMN2RXFP1
SCHEMBL6591158 0.87 F10 (1.00) F10TP53MAPTSMN1; SMN2RXFP1
SCHEMBL6593805 0.86 F10 (1.00) F10
SCHEMBL6591720 0.84 F10 (0.82) F10
SCHEMBL6593450 0.84 F10 (1.00) F10TP53MAPTSMN1; SMN2RXFP1
SCHEMBL6592001 0.84 F10 (0.81) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1040108-B1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AG (DE) 2004-02-25 EP claimed
US-6380221-B1 FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY BERLEX LABORATORIES, INC. 2002-04-30 US claimed
EP-1040108-B1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AG (DE) 2004-02-25 EP disclosed
US-6498185-B1 ENZYME FACTOR XA INHIBITORS BERLEX LABORATORIES, INC. 2002-12-24 US disclosed
US-6380221-B1 FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY BERLEX LABORATORIES, INC. 2002-04-30 US disclosed