Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.71 |
| ▸ | MAOA | P21397 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | AR | P10275 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | CASP3 | P42574 | 2/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18154594 | 0.99 | MAOB (0.70) | MAOBMAOAKDM4EALDH1A1KMT2A | |
| SCHEMBL28026514 | 0.96 | MAOB (0.70) | MAOBMAOAKDM4EALDH1A1KMT2A | |
| SCHEMBL8187998 | 0.92 | MAOB (0.68) | MAOBMAOAKDM4EALDH1A1KMT2A | |
| SCHEMBL18898659 | 0.88 | MAOB (0.73) | MAOBMAOAKDM4EALDH1A1KMT2A | |
| SCHEMBL10063475 | 0.87 | MAOB (0.74) | MAOBMAOAKDM4EALDH1A1KMT2A | |
| SCHEMBL6874186 | 0.86 | MAOB (0.71) | MAOBMAOAKDM4EALDH1A1KMT2A | |
| SCHEMBL11474761 | 0.86 | MAOB (0.71) | MAOBMAOAKDM4EALDH1A1KMT2A | |
| SCHEMBL12617399 | 0.85 | MAOB (0.70) | MAOBMAOAKDM4EALDH1A1KMT2A | |
| SCHEMBL18312160 | 0.85 | MAOB (0.70) | MAOBMAOAKDM4EALDH1A1KMT2A | |
| SCHEMBL6591353 | 0.85 | MAOB (0.70) | MAOBMAOAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829601-A | Coumarin derivative, preparation method and application of same | LANZHOU CHEM PHYS INST | 2015-08-12 | — | — | CN | claimed |
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-107602518-B | Coumarin-dithiocarbamate derivative and synthesis method thereof | 广西壮族自治区肿瘤防治研究所 | 2020-01-24 | — | — | CN | disclosed |
| CN-107737126-B | Application of coumarin-dithiocarbamate derivative in pharmacy | 广西壮族自治区肿瘤防治研究所 | 2020-01-24 | — | — | CN | disclosed |
| CN-104829601-A | Coumarin derivative, preparation method and application of same | LANZHOU CHEM PHYS INST | 2015-08-12 | — | — | CN | disclosed |
| CN-103254219-B | Copper fluoride (I) reagent as well as preparation method and application thereof | UNIV FUZHOU | 2015-06-03 | — | — | CN | disclosed |
| US-6689799-B1 | NON-NUCLEOSIDE-DERIVATIVE VIRICIDES | REPHARTOX (NL) | 2004-02-10 | — | — | US | disclosed |
| EP-1214315-B9 | 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF | REPHARTOX (NL) | 2004-01-02 | — | — | EP | disclosed |
| EP-1214315-B1 | 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF | REPHARTOX (NL) | 2003-05-02 | — | — | EP | disclosed |