⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL21899730 | 0.78 | OR51E2 (0.50) | — | |
| SCHEMBL1922460 | 0.76 | TSHR (0.42) | — | |
| SCHEMBL6597188 | 0.75 | — | — | |
| SCHEMBL107741 | 0.73 | — | — | |
| SCHEMBL193026 | 0.73 | — | — | |
| SCHEMBL6963 | 0.73 | — | — | |
| SCHEMBL264859 | 0.73 | — | — | |
| SCHEMBL7712935 | 0.73 | — | — | |
| SCHEMBL15355768 | 0.73 | — | — | |
| SCHEMBL805277 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300365-B | Blocked polyisocyanate composition, hydrophilic polyisocyanate composition, resin film, and laminate | 旭化成株式会社 | 2022-08-12 | — | — | CN | disclosed |
| CN-112752811-A | Coating film | 旭化成株式会社 | 2021-05-04 | — | — | CN | disclosed |
| CN-112300365-A | Blocked polyisocyanate composition, hydrophilic polyisocyanate composition, resin film, and laminate | 旭化成株式会社 | 2021-02-02 | — | — | CN | disclosed |
| CN-111183167-A | Blocked polyisocyanate composition and use thereof | 旭化成株式会社 | 2020-05-19 | — | — | CN | disclosed |
| EP-1284267-B1 | TRIAZOLE COMPOUNDS HAVING AMIDE LINKAGE | SANKYO CO (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-6653330-B2 | Such as 4'-chloro-4-(5-(3-(2,4-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4 -triazol-1-y)butyl)-1,3-dioxan-2-yl)-benzanilide; antifungal activity | SANKYO COMPANY, LIMITED (JP) | 2003-11-25 | — | — | US | disclosed |
| US-20030176480-A1 | For therapy and prophylaxis of fungal infections | SANKYO COMPANY, LIMITED (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1284267-A1 | TRIAZOLE COMPOUNDS HAVING AMIDE LINKAGE | Sankyo Company, Limited (JP) | 2003-02-19 | — | — | EP | disclosed |
| US-5998612-A | Antibiotic synthesis | MERCK SHARP & DOHME CORP. | 1999-12-07 | — | — | US | disclosed |
| EP-0078026-B1 | ANTIBIOTIC SYNTHESIS | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0078026-A2 | Antibiotic synthesis | MERCK & CO. INC. (US) | 1983-05-04 | — | — | EP | disclosed |