Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 13/20 | 0.47 |
| ▸ | ADK | P55263 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596904 | 0.86 | F10 (0.45) | PTPN11F10NR3C1SMN1; SMN2HTT | |
| SCHEMBL6591490 | 0.85 | F10 (0.59) | F10SMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL7590490 | 0.85 | F10 (0.44) | F10SMN1; SMN2NPSR1TSHRALDH1A1 | |
| SCHEMBL6591567 | 0.84 | F10 (0.59) | F10ALDH1A1 | |
| SCHEMBL6591209 | 0.83 | F10 (0.50) | F10SMN1; SMN2TSHR | |
| SCHEMBL6593519 | 0.81 | F10 (0.62) | F10MEN1KMT2ATSHRL3MBTL1 | |
| SCHEMBL6108686 | 0.81 | F10 (0.56) | F10 | |
| SCHEMBL6714046 | 0.81 | F10 (0.58) | F10 | |
| SCHEMBL4858776 | 0.79 | F10 (0.51) | F10SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6592051 | 0.79 | F2 (0.58) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |