Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.73 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594269 | 1.00 | TNF (0.73) | TNFNOD1RAB9AALDH1A1MAPT | |
| SCHEMBL6591636 | 0.84 | TNF (1.00) | TNFNOD1RAB9AALDH1A1MAPT | |
| SCHEMBL6591632 | 0.84 | TNF (1.00) | TNFNOD1RAB9AALDH1A1MAPT | |
| SCHEMBL6594250 | 0.83 | TNF (0.74) | TNFNOD1RAB9AALDH1A1MAPT | |
| SCHEMBL6597454 | 0.83 | TNF (0.75) | TNFNOD1RAB9AALDH1A1MAPT | |
| SCHEMBL6597450 | 0.83 | TNF (0.75) | TNFNOD1RAB9AALDH1A1MAPT | |
| SCHEMBL6594246 | 0.83 | TNF (0.74) | TNFNOD1RAB9AALDH1A1MAPT | |
| SCHEMBL6591507 | 0.81 | TNF (0.68) | TNFNOD1RAB9AALDH1A1MAPT | |
| SCHEMBL6591510 | 0.81 | TNF (0.68) | TNFNOD1RAB9AALDH1A1MAPT | |
| SCHEMBL6594078 | 0.81 | TNF (0.57) | TNFNOD1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |