Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | ERN1 | O75460 | 8/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594455 | 1.00 | MEN1 (0.60) | MEN1KMT2AERN1APPMAPT | |
| SCHEMBL6591204 | 0.92 | MEN1 (0.56) | MEN1KMT2AERN1APPMAPT | |
| SCHEMBL6591201 | 0.92 | MEN1 (0.56) | MEN1KMT2AERN1APPMAPT | |
| SCHEMBL6592755 | 0.80 | MEN1 (0.53) | MEN1KMT2AERN1APPMAPT | |
| SCHEMBL6589718 | 0.80 | MEN1 (0.53) | MEN1KMT2AERN1APPMAPT | |
| SCHEMBL6589713 | 0.80 | MEN1 (0.53) | MEN1KMT2AERN1APPMAPT | |
| SCHEMBL6592751 | 0.80 | MEN1 (0.53) | MEN1KMT2AERN1APPMAPT | |
| SCHEMBL4710116 | 0.80 | MEN1 (0.71) | MEN1KMT2AERN1APPMAPT | |
| SCHEMBL4710115 | 0.80 | MEN1 (0.71) | MEN1KMT2AERN1APPMAPT | |
| SCHEMBL6596145 | 0.77 | MAPT (0.60) | MEN1KMT2AERN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |