SCHEMBL6594845

SCHEMBL6594845

CCCC(Cl)CCCCCl

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.46
TDP1 Q9NUW8 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235676 0.97 TSHR (0.50) TSHRALDH1A1TDP1
SCHEMBL1784504 0.95
SCHEMBL18107310 0.90 TSHR (0.52) TSHRALDH1A1TDP1
SCHEMBL29173026 0.87 TSHR (0.57) TSHRALDH1A1TDP1
SCHEMBL29019044 0.87 TSHR (0.65) TSHRALDH1A1TDP1
SCHEMBL5197145 0.87 TSHR (0.65) TSHRALDH1A1TDP1
SCHEMBL11876816 0.87 TSHR (0.65) TSHRALDH1A1TDP1
SCHEMBL29019033 0.87 TSHR (0.65) TSHRALDH1A1TDP1
SCHEMBL28999212 0.86 TSHR (0.55) TSHRALDH1A1TDP1
SCHEMBL28993072 0.85 TSHR (0.62) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219840-A Crosslinked polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-12-31 CN disclosed
CN-119219824-A Crosslinked polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-12-31 CN disclosed
CN-116063345-B Phosphonic acid group monomer and preparation method thereof 中国石油化工股份有限公司 2024-08-06 CN disclosed
CN-116063626-B Anti-calcium shrinkage and expansion agent and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN disclosed
CN-116064016-B Scale inhibition anti-swelling shrinkage swelling agent and preparation method and application thereof 中国石油化工股份有限公司 2024-04-05 CN disclosed
CN-116063626-A Anti-calcium shrinkage and expansion agent and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN disclosed
CN-116064016-A Scale inhibition anti-swelling shrinkage swelling agent and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN disclosed
CN-116063345-A Phosphonic acid group monomer and preparation method thereof 中国石油化工股份有限公司 2023-05-05 CN disclosed
US-9738738-B2 Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group BRIDGESTONE CORPORATION (JP) 2017-08-22 US disclosed
US-20160289355-A1 POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP BRIDGESTONE CORPORATION (JP) 2016-10-06 US disclosed
EP-0915867-B1 THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS SOD CONSEILS RECH APPLIC (FR) 2004-10-06 EP disclosed
US-6107495-A REACTING SPECIFIED 1-(2- OR 3-THIENYL) CYCLOHEXANES WITH A 1,5-DIHALOPENTANE TO FORM CYCLIC (THIENYLCYCLOHEXYL)AMINES SUCH AS 2-ALKYL-(3-THIENYL)CYCLOHEXYL PIPERIDINE; USE AS INTERMEDIATES TO RADIOACTIVE LABELLED MOLECULES SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) 2000-08-22 US disclosed
EP-0915867-A1 THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) 1999-05-19 EP disclosed
WO-1998003498-A1 THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) 1998-01-29 WO disclosed
US-4060547-A FROM TETRAHYDROFURAN OR AN ACYCLIC GLYCOL, AND CARBON MONOXIDE, RHODIUM OR IRIDIUM-HALOGEN CATALYST MONSANTO COMPANY (US) 1977-11-29 US disclosed