Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591721 | 0.92 | P2RX1 (0.64) | P2RX1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27782904 | 0.86 | KDM1A (0.64) | P2RX1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27194529 | 0.85 | MEN1 (0.55) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL6591068 | 0.84 | MEN1 (0.55) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL491122 | 0.83 | KMT2A (0.57) | P2RX1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14345113 | 0.83 | P2RX1 (0.55) | P2RX1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17350395 | 0.82 | P2RX1 (0.60) | P2RX1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL492308 | 0.81 | KMT2A (0.56) | P2RX1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL491924 | 0.81 | KMT2A (0.63) | P2RX1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6590143 | 0.81 | MAPT (0.65) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |