Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594935 | 1.00 | SLC6A4 (0.30) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6594939 | 1.00 | SLC6A4 (0.30) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL6596983 | 0.76 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL6596988 | 0.76 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL6596986 | 0.76 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL6332876 | 0.63 | GRK2 (0.36) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL6332869 | 0.63 | GRK2 (0.36) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL6332872 | 0.63 | GRK2 (0.36) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13894692 | 0.62 | HTR2C (0.55) | SLC6A4 | |
| SCHEMBL1861451 | 0.61 | PSMB8 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204660-B1 | SEROTONERGIC BENZOTHIOPHENES | LILLY CO ELI (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1204660-A1 | SEROTONERGIC BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009126-A1 | SEROTONERGIC BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |