Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3284436 | 0.92 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP2C19TSHRNPC1 | |
| SCHEMBL24038017 | 0.89 | CYP2C19 (0.54) | CYP3A4CYP2C9CYP2C19TSHRNPC1 | |
| SCHEMBL21915824 | 0.89 | CYP2C19 (0.54) | CYP3A4CYP2C9CYP2C19TSHRNPC1 | |
| SCHEMBL1721615 | 0.89 | CYP2C19 (0.54) | CYP3A4CYP2C9CYP2C19TSHRNPC1 | |
| SCHEMBL304701 | 0.86 | CYP3A4 (0.58) | CYP3A4CYP2C9CYP2C19TSHRNPC1 | |
| SCHEMBL29781191 | 0.86 | CYP3A4 (0.58) | CYP3A4CYP2C9CYP2C19TSHRNPC1 | |
| SCHEMBL24707932 | 0.86 | CYP3A4 (0.58) | CYP3A4CYP2C9CYP2C19TSHRNPC1 | |
| SCHEMBL3525474 | 0.85 | CYP3A4 (0.57) | CYP3A4CYP2C9CYP2C19TSHRNPC1 | |
| SCHEMBL8028321 | 0.85 | CYP3A4 (0.57) | CYP3A4CYP2C9CYP2C19TSHRNPC1 | |
| SCHEMBL7373506 | 0.84 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981526-B1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-02-25 | — | — | EP | disclosed |
| EP-0981526-A1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-01 | — | — | EP | disclosed |
| CN-1221415-A | Novel antidiabetic compounds having hypolipidemic and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDY RESEARCH FOUNDATION (IN) | 1999-06-30 | — | — | CN | disclosed |
| US-5889025-A | Antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-30 | — | — | US | disclosed |
| WO-1997041119-A1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-11-06 | — | — | WO | disclosed |