Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 1.00 |
| ▸ | CDK4 | P11802 | 6/20 | 0.74 |
| ▸ | CDK1 | P06493 | 2/20 | 0.53 |
| ▸ | IKBKB | O14920 | 3/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4855523 | 0.91 | CDK2 (0.83) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL4820462 | 0.89 | CDK2 (0.80) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL4817036 | 0.88 | CDK2 (0.79) | CDK2CDK4CDK1IKBKB | |
| Dimethylamine SCHEMBL6593494 | 0.88 | CDK2 (0.78) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL6593492 | 0.85 | CDK2 (0.74) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL4818566 | 0.85 | CDK2 (1.00) | CDK2CDK4CDK1 | |
| SCHEMBL6596039 | 0.84 | CDK2 (0.72) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL4817051 | 0.84 | CDK2 (0.72) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL6364557 | 0.84 | CDK2 (0.72) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL4821591 | 0.84 | CDK2 (0.72) | CDK2CDK4CDK1IKBKBSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351958-B1 | IMIDAZOLO-5-YL-2-ANILINO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF THE CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2004-06-16 | — | — | EP | disclosed |